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Avelox Interactions
When you take certain medications with Avelox, interactions may occur that could increase your risk of tendon rupture, bleeding, QT prolongation, and central nervous system stimulation problems. Some of the medications that may cause an interaction include warfarin, sucralfate, quinapril, and nonsteroidal anti-inflammatory drugs (NSAIDs). Interactions with Avelox can also prevent the antibiotic from being absorbed into the bloodstream.
Avelox® (moxifloxacin) can potentially interact with a few other medications. Some of the medicines that may lead to Avelox drug interactions include:
- Aluminum, calcium, or magnesium antacids (Alternagel®, Gaviscon®, Maalox®, Mylanta®, Tums®, and many others)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Ovapred®, Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®, Aristospan®)
- Didanosine (Videx®)
- Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
- Ibuprofen (Motrin®, Advil®)
- Naproxen (Naprosyn®) or naproxen sodium (Aleve®, Anaprox®, Naprelan®)
- Diclofenac (Cataflam®, Voltaren®)
- Indomethacin (Indocin®)
- Nabumetone (Relafen®)
- Oxaprozin (Daypro®)
- Celecoxib (Celebrex®)
- Meloxicam (Mobic®)
- Etodolac (Lodine®)
- Ketoprofen (Orudis®)
- Ketorolac (Toradol®)
- Oral typhoid vaccine
- QT-prolonging medications (drugs that cause an irregular heart rhythm known as QT prolongation)
- Quinapril (Accupril®) or quinapril-HCTZ (Accuretic®)
- Sevelamer (Renagel®, Renvela®)
- Sucralfate (Carafate®)
- Vitamins that contain aluminum, calcium, magnesium, zinc, or iron
- Warfarin (Coumadin®, Jantoven®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



