Azactam Side Effects

Nausea, diarrhea, and reactions at the injection site are among the common side effects reported with Azactam. Certain problems are more serious and should be reported to your healthcare provider. These can include bloody diarrhea, any type of skin rash, and fainting. Fortunately, most reactions to this medicine are minor and easy to treat.


An Introduction to Azactam Side Effects

As with any medicine, Azactam® (aztreonam injection) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Azactam. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Azactam

The prescribing information for most medications provides details on potential side effects, including the exact percentage of people who experienced each potential side effect in clinical trials. The prescribing information for most older medications, including Azactam, only includes vague information for potential side effects, with few percentages given.
Based on the prescribing information, the most commonly reported side effects of Azactam include:
  • Discomfort and swelling at the injection site when the medication was given as an intramuscular (IM) injection (an injection into a muscle) -- in about 2.4 percent of people
  • Reactions such as pain, swelling, and redness at the site of the injection when the medication was given as an intravenous (IV) injection (an injection into a vein) -- about 1 percent.
Other common side effects, occurring in 1 percent to 1.3 percent of people, include:
Other possible bothersome side effects, reported in less than 1 percent of people, may include but are not limited to:
  • Abdominal (stomach) cramps
  • Insomnia
  • Dizziness
  • Muscle aches
  • Ringing in the ears
  • Double vision
  • Changes in taste
  • Sneezing
  • Stuffy nose
  • Bad breath
  • Breast tenderness
  • Weakness
  • Headache
  • Fever
  • Sudden warmth and redness of the face, neck, and chest (flushing)
  • Tingling, pricking, or burning sensations of the skin
  • Increased sweating
  • A general sense of discomfort or ill-being
  • Mouth ulcer or sores.  
In children, the most commonly reported bothersome side effects include:
  • Pain at the IV injection site -- in up to 12 percent of children
  • Rash -- up to 4.3 percent
  • Redness at the IV injection site -- up to 2.9 percent
  • Swelling of the vein at the IV injection site -- up to 2.1 percent
  • Diarrhea -- up to 1.4 percent
  • Fever -- up to 1 percent.

Azactam Antibiotic Information

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