Can I Take My Current Medicines With Bactrim?

Thiazide Diuretics
There have been reports that taking Bactrim with a thiazide diuretic may increase the risk of low blood platelets. Be sure to watch for any signs of low platelets, such as easy bruising or bleeding.
 
Tricyclic Antidepressants
Bactrim might decrease the effectiveness of tricyclic antidepressants. Be sure to let your healthcare provider know if you think your antidepressant is not working as well as usual.
 
Warfarin
There have been reports that combining Bactrim with warfarin may increase the risk of bleeding. If you take these medications together, your healthcare provider may need to monitor you more closely.
 

Final Thoughts on Bactrim Drug Interactions

Not all Bactrim drug interactions were discussed in this article. Compared to many other medications, Bactrim has a high likelihood for drug interactions. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with Bactrim that may apply to you.
 
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