Cedax Drug Interactions

Birth control pills, the oral typhoid vaccine, and certain antibiotics may not be safe to combine with Cedax. Drug interactions such as these may decrease the effectiveness of the products or lead to potentially serious side effects. You can help minimize your risk by letting your healthcare provider know about all vitamins, supplements, and other medications you are taking before using Cedax.


An Overview of Interactions With Cedax

Cedax® (ceftibuten) may react with a few other products. Some of the drugs that can interact with Cedax include but are not limited to:
  • Aminoglycoside antibiotics, such as:
    • Amikacin (Amikin®)
    • Gentamicin
    • Kanamycin (Kantrex®)
    • Neomycin (Neo-Fradin®)
    • Streptomycin
    • Tobramycin

Cedax Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cedax is combined with any of the drugs listed above.
Aminoglycoside Antibiotics
Combining Cedax with an aminoglycoside antibiotic may increase the risk of kidney damage. Nonetheless, in some very serious situations, such combinations may be used when the possible benefits outweigh the likely risks.
Birth Control Pills
Despite the long-standing belief that antibiotics interact with birth control pills, several studies have shown that most antibiotics do not increase the risk of pregnancy in women taking birth control pills. Nevertheless, there have been reports of birth control pill failure in women who have taken antibiotics.
Ask your healthcare provider about whether you need to use a backup method of birth control while taking Cedax (see Antibiotics and Birth Control Pills for more information). If it is very important to you to avoid pregnancy, you might consider using a backup method just to be safe.
Oral Typhoid Vaccine
Like other antibiotics, Cedax may decrease the effectiveness of the oral typhoid vaccine. If you have taken Cedax recently or are currently taking it, your oral typhoid vaccine may need to be postponed for at least a day after taking the drug.
Probenecid can decrease the body's ability to remove Cedax from the blood, potentially leading to high Cedax blood levels. Talk with your healthcare provider before taking these medications together.
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Cedax Antibiotic Information

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