You should talk with your healthcare provider prior to receiving this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- An allergy to cephalosporin or penicillin antibiotics
- Any other allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Ancef and Pregnancy)
- Breastfeeding (see Ancef and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Cefazolin to learn more, including information on who should not use the drug.)
As mentioned, cefazolin is a cephalosporin antibiotic. Cephalosporins are part of a larger group of medications known as beta-lactam antibiotics, named after the ring-like "lactam" structure of these drugs. Cefazolin works by stopping bacteria from making cell walls, which eventually causes the bacteria to die. Cephalosporins are related to penicillin. Cefazolin is usually classified as a "first-generation" cephalosporin.
Some general considerations to keep in mind during treatment with cefazolin include the following:
- This medication is given by IV or by intramuscular injection. It is usually given every 6 to 12 hours.
- For serious infections, it is usually best to give this drug by IV rather than an intramuscular injection.
- Cefazolin is often given for a few days after the infection has cleared up. For serious infections, an even longer treatment course may be recommended.