Important Information for Your Healthcare ProviderYou should talk with your healthcare provider prior to receiving this medication if you have:
- Kidney disease, such as kidney failure (renal failure)
- An allergy to cephalosporin or penicillin antibiotics
- Any other allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Claforan and Pregnancy)
- Breastfeeding (see Claforan and Breastfeeding).
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Cefotaxime to learn more, including information on who should not use the drug.)
How Does Cefotaxime Work?Cefotaxime is a cephalosporin antibiotic. Cephalosporins are part of a larger group of medications known as beta-lactam antibiotics, named after the ring-like "lactam" structure of these drugs. Cefotaxime works by stopping bacteria from making cell walls, which eventually causes the bacteria to die. Cephalosporins are related to penicillin. Cefotaxime is usually classified as a "third-generation" cephalosporin.
When and How to Use This MedicineSome general considerations to keep in mind during treatment with cefotaxime include the following:
- This medication is given by IV or by intramuscular injection. It can be given as a single dose for less serious infections, or it may be given as multiple doses every 4 to 12 hours for more serious infections.
- For serious infections, it is usually best to give this drug by IV rather than an intramuscular injection.
- Cefotaxime is often given for a few days after the infection has cleared up. For serious infections, an even longer treatment course may be recommended.