Drug Interactions With Cefoxitin

Birth Control Pills
Despite the longstanding belief that antibiotics interact with birth control pills, several studies have shown that most antibiotics do not increase the risk of pregnancy in women taking birth control pills.
 
Nevertheless, there have been reports of birth control pill failure in women who have taken antibiotics. Ask your healthcare provider about whether or not you need to use a backup method of birth while using cefoxitin (see Antibiotics and Birth Control Pills for more information). If it is important to you to avoid pregnancy, you might consider using a backup method of birth control just to be safe.
 
Oral Typhoid Vaccine
Like other antibiotics, cefoxitin may decrease the effectiveness of the oral typhoid vaccine. If you have received cefoxitin recently, or are currently using cefoxitin, your oral typhoid vaccine may need to be postponed for at least a day after receiving cefoxitin.
 
Probenecid
Probenecid can decrease the body's ability to remove cefoxitin from the blood, potentially leading to high cefoxitin blood levels. Talk with your healthcare provider before using these medications together.
 
Warfarin
There have been reports that cephalosporin antibiotics, including cefoxitin, can increase the anticoagulant effects of warfarin. If you are taking warfarin, very close monitoring will be necessary during cefoxitin treatment and for a while after treatment ends. Your warfarin dosage may need to be temporarily adjusted.
 

Final Thoughts

It is possible that not all cefoxitin drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
 

Cefoxitin Drug Information

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