Cefzil Warnings and Precautions

People who have a penicillin allergy may also be allergic to Cefzil. There are also some safety precautions for people who have phenylketonuria, as well as warnings for those who have kidney problems. Some people may also have an increased risk for developing problems like potentially life-threatening diarrhea, serious allergic reactions, and other dangerous complications.

 

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Cefzil® (cefprozil) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • An allergy to cephalosporin or penicillin antibiotics
  • Phenylketonuria
  • Any other allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Cefzil

Some warnings and precautions to be aware of prior to using this medication include the following:
 
  • Cefzil contains an antibiotic that belongs to the cephalosporin group of antibiotics, which are related to penicillin antibiotics. Some people who are allergic to penicillin will also be allergic to Cefzil. An allergic reaction can be quite dangerous. Let your healthcare provider know immediately if you notice any signs of an allergic reaction, such as:
    • A rash
    • Itching
    • Hives
    • Wheezing
    • Swelling of the mouth or lips
    • Difficulty breathing.
 
  • Make sure your healthcare provider knows if you have kidney disease, as the kidneys excrete Cefzil from the body. If your kidneys are not functioning well, you will need a lower and/or less-frequent Cefzil dosage.
 
  • Let your healthcare provider know if you experience bloody or watery diarrhea. While diarrhea is a common side effect of Cefzil, bloody or watery diarrhea may be a sign of a serious reaction to the drug that can occur when certain bacteria (Clostridium difficile) overgrow in the colon. This severe reaction can occur long after you stop using Cefzil and can be life-threatening.
 
  • Cefzil oral suspension (liquid) contains 28 mg of phenylalanine per teaspoonful (per 5 mL). This is important for people with phenylketonuria, who must monitor and limit their phenylalanine intake.
 
  • Antibiotics can sometimes cause yeast infections, as they can get rid of "good" bacteria that help protect against yeast infections. Let your healthcare provider know if you develop a vaginal yeast infection or thrush (a yeast infection of the mouth) during treatment.
 
  • Cefzil should not be used to treat viruses, such as the common cold or the flu. This drug is completely ineffective for treating viruses, and such use can lead to bacterial resistance.
   
  • Cefzil is a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are currently unknown. Talk to your healthcare provider about the risks and benefits of using this medicine when pregnant (see Cefzil and Pregnancy for more information).
 
  • This medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk to your healthcare provider before beginning treatment (see Cefzil and Breastfeeding for more information).
 
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