Precautions and Warnings With Ciprofloxacin/Hydrocortisone

If your symptoms do not improve within a week of taking ciprofloxacin/hydrocortisone, contact your healthcare provider, as you may need a different medication. In addition, this medication can cause a fungal or yeast infection, although this is rare. Ciprofloxacin/hydrocortisone precautions and warnings also apply to people with certain medical conditions, as well as women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using ciprofloxacin/hydrocortisone (Cipro® HC) if you have:
  • A hole in your eardrum or have ear tubes
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
In addition, tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Ciprofloxacin/Hydrocortisone Warnings and Precautions

Some warnings and precautions to be aware of prior to using this drug include the following:
  • Ciprofloxacin/hydrocortisone is an ear drop and should only be used in the ears. Do not take it by mouth, put it in your nose or eyes, or apply it to your skin.
  • Ciprofloxacin/hydrocortisone does not kill all the types of organisms that may cause an ear infection. Therefore, if your infection seems to get worse, or if it has not improved within a week, talk to your healthcare provider. You may need a different medication.
  • In rare cases, this drug may cause a fungal or yeast infection. Contact your healthcare provider if you experience persistent discomfort or itching in your ears, or notice pus coming from your ears. Also, contact your healthcare provider if you notice white patches in your mouth or throat or flaky, itchy, or red skin.
  • When taken orally, medications like ciprofloxacin (one of the active ingredients in this product) have been reported to cause severe allergic reactions. Seek immediate medical attention if you develop any signs of an allergic reaction, such as:
    • Rash or hives
    • Itching
    • Swelling of the lips or throat
    • Wheezing
    • Difficulty breathing.
  • Ciprofloxacin/hydrocortisone is unlikely to react with other medications (see Drug Interactions With Ciprofloxacin/Hydrocortisone).
  • Ciprofloxacin/hydrocortisone is a pregnancy Category C medication, which means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Cipro HC and Pregnancy for more information).
  • It is unknown if this medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk to your healthcare provider before beginning treatment (see Cipro HC and Breastfeeding).
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Ciprofloxacin/Hydrocortisone Drug Information

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