Taking Ciprofloxacin With Other Drugs

Sevelamer
Sevelamer can bind to ciprofloxacin in the digestive tract, decreasing the amount that is absorbed into the bloodstream. You should take ciprofloxacin at least one hour before or three hours after taking sevelamer.
 
Sucralfate
Sucralfate can bind to ciprofloxacin in the digestive tract, decreasing the amount that is absorbed into the bloodstream. You should take your ciprofloxacin dose at least four hours before or six hours after taking sucralfate.
 
Sulfonylureas
There have been reports of changes in blood sugar levels (both low and high) in people taking sulfonylureas with ciprofloxacin. Low blood sugar levels (hypoglycemia) may be more likely to occur within the first couple of days of beginning ciprofloxacin treatment, while high blood sugar levels (hyperglycemia) may be more likely to occur after several days.
 
If you take a sulfonylurea, your healthcare provider may recommend that you check your blood sugar levels more often while taking ciprofloxacin.
 
Theophylline
Ciprofloxacin may increase the level of theophylline in your blood, potentially increasing your risk for serious side effects, such as seizures. If you take these medications together, your healthcare provider may want to monitor the level of theophylline in your blood.
 
Tizanidine
Ciprofloxacin may increase the amount of tizanidine in your blood, increasing your risk for side effects, such as sedation or low blood pressure (hypotension). The manufacturer of ciprofloxacin recommends that these drugs not be taken together. However, if your healthcare provider recommends that you take tizanidine with ciprofloxacin, you may need to be watchful for tizanidine side effects.
 
Typhoid Vaccine
Antibiotics, including ciprofloxacin, may decrease the effectiveness of the typhoid vaccine. However, this drug interaction only occurs with the oral typhoid vaccine. It is generally recommended that the oral typhoid vaccine be postponed for at least a day after finishing ciprofloxacin.

Ciprofloxacin Antibiotic Information

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