Medicines That Interfere With Erythromycin

Erythromycin Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when erythromycin is combined with any of the drugs listed above.
 
Calcium Channel Blockers
Erythromycin may increase the level of these medications in the blood, increasing the risk of serious calcium channel blocker side effects. Check with your healthcare provider before taking erythromycin with a calcium channel blocker.
 
Carbamazepine
Erythromycin may increase the level of carbamazepine in your blood, perhaps increasing your chance for side effects of carbamazepine. Your healthcare provider may want to monitor the level of carbamazepine in your blood during treatment if you have to take these medications together.
 
Certain Benzodiazepines
Erythromycin could increase the level of some (but not all) benzodiazepines in the blood, increasing the risk of side effects. Check with your healthcare provider before combining these medications.
 
Colchicine
Erythromycin can increase the level of colchicine in your blood, increasing your risk of colchicine toxicity. Do not take these medications together without your healthcare provider's approval and supervision.
 
Digoxin
Erythromycin could increase the level of digoxin in your blood, perhaps increasing your chance for side effects of digoxin. Your healthcare provider may want to monitor the level of digoxin in your blood during treatment if you have to take these medications together.
 
Ergot Medications
Erythromycin increases the risk of toxicity from ergot medications. In general, this combination should be avoided.
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