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Factive Drug Interactions
If corticosteroids, warfarin, or products that contain aluminum, calcium, or magnesium are taken with Factive, drug interactions can occur. These interactions can lead to problems such as decreased effectiveness of Factive or an increased risk for side effects. To prevent these and other potentially serious complications, you may need to take the medications at different times.
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Factive® (gemifloxacin mesylate) is a prescription medication used to treat bacterial infections, including bronchitis and pneumonia. This medication may potentially react with several other medications.
Some of the drugs that may lead to interactions with Factive include but are not limited to:
- Aluminum, calcium, or magnesium antacids (Alternagel®, Gaviscon®, Maalox®, Mylanta®, Tums®, and many others)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Ovapred®, Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®, Aristospan®)
- Didanosine (Videx®)
- Medications that cause a certain change in the heart rhythm known as QT prolongation (see QT-Prolonging Medications for a list of such medications)
- Probenecid
- Sevelamer (Renagel®, Renvela®)
- Sucralfate (Carafate®)
- Vitamins or supplements that contain aluminum, calcium, magnesium, zinc, or iron
- Warfarin (Coumadin®, Jantoven®).
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD