Levaquin Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
Levaquin is combined with any of the drugs listed above.
Aluminum, Calcium, or Magnesium Antacids
Aluminum,
calcium, and magnesium can bind to Levaquin in the digestive tract, preventing it from being absorbed into the bloodstream. Separate your Levaquin dose and any products that contain aluminum, calcium, or magnesium by as much time as possible (by two hours at the very least).
Certain Arrhythmia Medications
Combining Levaquin with certain arrhythmia medications can increase the risk of a dangerous change in heart rhythm known as QT prolongation. Check with your healthcare provider before taking these medications together.
Corticosteroids
Corticosteroids seem to increase the risk of tendon rupture due to Levaquin. If your healthcare provider recommends taking Levaquin with a corticosteroid, be sure to watch for any signs of tendon rupture (such as pain or tenderness).
Diabetes Medications
There have been reports of changes in blood sugar (both high and low) in people taking
diabetes medications and Levaquin together. Your healthcare provider may recommend that you check your blood sugar more often while taking Levaquin.
Didanosine
Some forms of
didanosine can bind to Levaquin in the digestive tract, preventing it from being absorbed into the bloodstream. Separate your Levaquin dose and didanosine by as much time as possible (by two hours at the very least). Not all forms of didanosine interact with Levaquin, so be sure to ask your pharmacist about this possible interaction with your particular didanosine product.