Antibiotics Home > Drug Interactions With Cefoxitin

When using cefoxitin, people should talk to their healthcare provider about all other medicines, vitamins, or herbal supplements they are taking. Drug interactions can occur when cefoxitin is combined with certain products, including birth control pills, aminoglycoside antibiotics, and warfarin. In some cases, reactions such as these may increase your risk for side effects or interfere with the effectiveness of the medications.

An Overview of Cefoxitin Interactions

Cefoxitin (Mefoxin®) is a prescription medication licensed to treat certain bacterial infections. It can potentially react with other medications. Some of the products that may lead to cefoxitin drug interactions include:
  • Aminoglycoside antibiotics, such as:
    • Amikacin (Amikin®)
    • Gentamicin
    • Kanamycin (Kantrex®)
    • Neomycin (Neo-Fradin®)
    • Streptomycin
    • Tobramycin

More Detail on Drug Interactions With Cefoxitin

The following sections explain in detail the potentially negative reactions that can occur when cefoxitin is combined with any of the drugs listed above.
Aminoglycoside Antibiotics
Combining cefoxitin with an aminoglycoside antibiotic may increase the risk of kidney damage. Nonetheless, in some very serious situations, this combination may be used when the possible benefits outweigh the likely risks.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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