Antibiotics Home > Precautions and Warnings With Cefuroxime Axetil

You may not be able to use cefuroxime axetil if you have kidney disease or certain allergies. Being aware of cefuroxime axetil's precautions and warnings can help ensure a safe treatment process. Before taking this antibiotic, make sure your healthcare provider has a list of all medications you are taking and any medical conditions you have.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking cefuroxime axetil (Ceftin®) if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • An allergy to cephalosporin or penicillin antibiotics
  • Any other allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all of the medicines you are taking, including prescription and nonprescription medications, vitamins, and herbal supplements.

Specific Cefuroxime Axetil Warnings and Precautions

Some warnings and precautions to be aware of prior to taking cefuroxime axetil include the following:
  • Cefuroxime axetil contains an antibiotic that belongs to the cephalosporin group of antibiotics (which are related to penicillin antibiotics). Some people who are allergic to penicillins will also be allergic to cefuroxime axetil. Let your healthcare provider know immediately if you notice any signs of an allergic reaction, such as a rash, itching, hives, wheezing, swelling of the mouth or lips, or difficulty breathing. An allergic reaction to cefuroxime axetil can be very dangerous.
  • Let your healthcare provider know if you experience bloody or watery diarrhea. While diarrhea is a common side effect of cefuroxime axetil, bloody or watery diarrhea may be a sign of a serious reaction to cefuroxime axetil that can occur when certain bacteria (Clostridium difficile) overgrow in the colon. This severe reaction can occur long after you stop taking cefuroxime axetil and can cause life-threatening complications.
  • Make sure your healthcare provider knows if you have kidney disease, as cefuroxime axetil may not be a good choice for people with kidney disease.
  • Sometimes, antibiotics (including cefuroxime axetil) can cause yeast infections, as they can get rid of "good" bacteria that help protect against yeast infections. Let your healthcare provider know if you develop a vaginal yeast infection or thrush (a yeast infection of the mouth) while taking cefuroxime axetil.
  • Cefuroxime axetil should not be used to treat viruses, such as the common cold or the flu. Cefuroxime axetil is completely ineffective for treating viruses, and such use can lead to bacterial resistance to cefuroxime axetil.
  • It is very important to take cefuroxime axetil exactly as prescribed. Skipping doses or stopping cefuroxime axetil too early (even if you feel better) can lead to bacterial resistance to this medication.
  • Cefuroxime axetil oral suspension contains phenylalanine. This is important for people with phenylketonuria, who must monitor their phenylalanine intake. Cefuroxime axetil tablets do not contain phenylalanine.
  • Cefuroxime axetil can interact with other medications (see Drug Interactions With Cefuroxime Axetil).
  • Cefuroxime axetil is considered a pregnancy Category B medication. This means that cefuroxime axetil is probably safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using cefuroxime axetil during pregnancy (see Ceftin and Pregnancy for more information).
  • Cefuroxime axetil passes through breast milk. Therefore, if you are breastfeeding a child, make sure to talk with your healthcare provider about using this medication (see Ceftin and Breastfeeding for more information).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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