Antibiotics Home > Dicloxacillin

Dicloxacillin is available only in generic form and is used to treat a variety of bacterial infections. This prescription antibiotic comes as capsules that are usually taken every six hours. Your dosage will depend on a number of factors, such as your age and other medical conditions you have. Side effects are possible and may include nausea, diarrhea, and allergic reactions.


What Is Dicloxacillin?

Dicloxacillin sodium is a prescription antibiotic licensed to treat a number of different infections. Specifically, it is used for infections caused by Staphylococci bacteria that produce penicillinase, an enzyme than can destroy penicillin.
(Click Dicloxacillin Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Dicloxacillin is available only as a generic product and is made by various manufacturers (see Generic Dicloxacillin).

How Does Dicloxacillin Work?

Dicloxacillin is a penicillin antibiotic. Penicillins are part of a larger group of medications known as beta-lactam antibiotics, which are named after the ring-like "lactam" structure of these drugs. Dicloxacillin works by stopping bacteria from making cell walls, which eventually causes the bacteria to die.
More specifically, dicloxacillin is a penicillinase-resistant penicillin. Some bacteria produce penicillinase, an enzyme that destroys the beta-lactam structure of penicillin, making it and other similar antibiotics ineffective for treating infections due to such bacteria. Dicloxacillin is resistant to penicillinase.
However, such bacteria (notably, methicillin-resistant Staphylococcus aureus, or MRSA) have developed resistance against dicloxacillin and other penicillinase-resistant penicillins. Dicloxacillin is ineffective against MRSA.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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