Antibiotics Home > Factive

A healthcare provider may prescribe Factive for treating bacterial cases of bronchitis or pneumonia. This medication is a type of antibiotic and works by interfering with bacteria's ability to multiply. It comes in the form of a tablet, and is typically taken once daily. Possible side effects may include headaches, nausea, and diarrhea.

What Is Factive?

Factive® (gemifloxacin mesylate) is a prescription medication that belongs to a group of drugs called fluoroquinolones, or "quinolones" for short. Like other quinolones, Factive is an antibiotic. It is approved to treat certain types of bronchitis and pneumonia.
(Click Factive Uses for more information on this topic, including possible off-label uses.)

Who Makes This Medication?

Factive is made by Cornerstone Therapeutics, Inc.

How Does Factive Work?

Factive works to treat bacterial infections by killing the bacteria that cause the infections. Specifically, Factive interferes with two bacterial enzymes called topoisomerase IV and DNA gyrase. These enzymes are necessary for the bacteria to copy and repair DNA, which are critical steps needed for the bacteria to multiply.

When and How to Use It

Some general considerations to keep in mind during treatment with Factive include the following:
  • Factive comes in tablet form. It is usually taken once a day.
  • This medication can be taken with or without food. Take it with a glass of water.
  • Try to take Factive at the same time each day to maintain an even level in your blood.
  • Swallow Factive tablets whole -- do not crush or chew them. Tell your healthcare provider if you cannot swallow the tablets. You may break the tablets in half (along the break lines), if necessary.
  • Make sure you drink plenty of fluids to stay well hydrated during Factive treatment.
  • Factive is an antibiotic used to treat bacterial infections. It will not treat infections caused by viruses, such as the common cold or flu.
  • You should start to feel better within a couple of days of treatment. However, this does not mean your infection is gone. Make sure you finish the entire course of this medicine. Stopping it too early may cause your symptoms to return or lead to antibiotic resistance.
  • For the medication to work properly, it must be used as prescribed.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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