Antibiotics Home > Omnicef Drug Interactions

Negative Omnicef drug interactions can cause your body to metabolize the medicines differently than intended and result in either increased or decreased levels of the antibiotic in your system. Medications that can interact with Omnicef include probenecid, iron supplements, and certain antacids. If Omnicef drug interactions occur, your healthcare provider may monitor your progress more closely and adjust your dosage of these drugs.

Omnicef Drug Interactions: An Introduction

Omnicef® (cefdinir) has a limited number of medicines that it is known to interact with. Omnicef drug interactions can include but are not limited to:
  • Probenecid (Benemid®, Probalan®)
  • Antacids containing aluminum or magnesium, such as Maalox®, Mylanta®, Riopan®, Gelusil®, Rolaids®, ALternaGEL®, Amphojel®, and others
  • Iron supplements (including multivitamins) or foods high in iron.

More Information on Omnicef Interactions

The following sections explain in detail the potentially negative interactions that can occur when Omnicef is taken with any of the drugs listed above.
If you are taking both Omnicef and probenecid, your body may metabolize these drugs differently than intended. This can significantly increase the amount of Omnicef in your system. Your healthcare provider may choose to monitor your progress more closely and adjust your dosage accordingly if this occurs.
Aluminum or Magnesium Antacids
If Omnicef and antacids made with aluminum or magnesium are taken together, less Omnicef may be absorbed into your body. To prevent this interaction, take the antacids at least two hours before or two hours after taking the Omnicef.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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