Antibiotics Home > Oxacillin Side Effects

Because oxacillin is an older medication, its published side effect information is not very specific. However, we do know that some of the most commonly reported side effects of this drug include diarrhea, nausea, and vomiting. This antibiotic can also cause some potentially serious reactions, such as seizures, blood in the urine, or a rash, which require urgent medical treatment.

An Introduction to Side Effects of Oxacillin

Just like any medicine, oxacillin can cause side effects. However, not everyone who receives the drug will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with oxacillin. Your healthcare provider can discuss a more complete list with you.)

Possible Side Effects of Oxacillin

For most newer medications, the prescribing information provides highly detailed information on potential side effects, carefully describing the exact percentages of people who developed each side effect during clinical studies.
However, the same is not true for older medications; the prescribing information for most older medications includes only vague information about possible side effects, with no exact percentages. Oxacillin is an older medication, and detailed information about potential side effects is not available. 
Some of the possible bothersome, but not usually dangerous, side effects of oxacillin may include:
  • Nausea
  • Vomiting
  • Diarrhea
  • Canker sores
  • Black, hairy tongue (which is disturbing, but temporary and not dangerous).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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