Antibiotics Home > Drug Interactions With Retapamulin

Retapamulin (Altabax®) ointment is unlikely to have serious interactions with other drugs. This prescription antibiotic is used for impetigo treatment.
Studies have shown that retapamulin is broken down (metabolized) by certain liver enzymes known as CYP 3A4. Many other medications can interfere with the activity of CYP 3A4, potentially increasing or decreasing the level of the medication in the blood. However, because so little retapamulin reaches the bloodstream, and because the antibiotic works directly on the skin, it is unlikely that such interactions would cause any problems.
Nonetheless, it is still a good idea to ask about any drug interactions with retapamulin that may apply to you. If you must apply other skin products, ask your healthcare provider whether the products can be applied with retapamulin or if you must stop using the other products temporarily.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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