Antibiotics Home > Teflaro and Pregnancy
When Teflaro (ceftaroline) was given to pregnant animals, it did not appear to cause any problems in the offspring. As a result, this antibiotic is generally considered safe for use during pregnancy. However, because humans may respond differently to medications than animals do, talk to your healthcare provider about the benefits and risks in your particular situation.
Teflaro® (ceftaroline fosamil) is a prescription antibiotic given intravenously (by IV). Like other cephalosporin antibiotics, Teflaro is usually considered safe for use during pregnancy.
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Teflaro is classified as a pregnancy Category B medication.
Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause harm to the fetus in animal studies. Medications that have been shown to be safe for use in pregnancy in humans but have caused problems in laboratory animals are also given a Category B rating.
Teflaro was given a pregnancy Category B rating because studies in pregnant rats did not appear to cause any problems. Studies in rabbits showed a few problems, such as miscarriages and skeletal variations, but these problems were probably due to the toxicity of the drug in the mother; many of the mother rabbits died or were very near death.
However, it is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category B medicine, including Teflaro, should be given to a pregnant woman only if her healthcare provider believes that the benefits to the woman outweigh any possible risks to her unborn child.