Antibiotics Home > Can I Take My Medications With Tetracycline?

Penicillin
It is recommended that you not take penicillin and tetracycline at the same time. This is because tetracycline may reduce penicillin's ability to fight an infection. If you are already taking tetracycline, talk with your healthcare provider about alternatives to penicillin.
 
Triazolam, Midazolam, Cisapride, Cyclosporine, Mirtazapine, Nefazodone, Quinidine, Sildenafil, Nateglinide, Tacrolimus, Venlafaxine, Lovastatin, Simvastatin, Pimozide, Thioridazine, Mesoridazine, and Calcium Channel Blockers
If you are taking both tetracycline and any of the medications listed above, your body may metabolize them differently than intended and significantly increase the levels of these drugs in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.
 
Bismuth Subsalicylate, Barbiturates, Sucralfate, Quinapril, Didanosine, Phenytoin, Carbamazepine, Nafcillin, Aminoglutethimide, and Nevirapine
If you are taking both tetracycline and any of the medications listed above, your body may metabolize them differently than intended and significantly decrease the amount of tetracycline in your system. Your healthcare provider may choose to monitor your progress and adjust your dosage accordingly.
 

Tetracycline Drug Interactions: Summary

It is possible that not all potential tetracycline drug interactions were discussed is this article. Therefore, you should talk with your doctor or pharmacist about specific drug interactions with tetracycline that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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