Specific Medicines That Interfere With Minocycline

More Information on Minocycline Interactions

The following sections explain in detail the potentially negative interactions that can occur when minocycline is taken with any of the medications listed above.
 
Aluminum/Calcium/Magnesium/Iron Products
If minocycline is taken with products containing aluminum, calcium, magnesium, or iron, your body may not absorb minocycline adequately. To avoid this interaction, it is a good idea to take minocycline at least two hours before or six hours after any products with aluminum, calcium, magnesium, or iron.
 
Bile Acid Sequestrants
Bile acid sequestrants may bind to minocycline in the digestive tract, preventing it from being properly absorbed. This may make minocycline less effective. Separate your doses of minocycline and a bile acid sequestrant by as much time as possible (at least two hours or more).
 
Birth Control Pills
Despite the longstanding belief that antibiotics interact with birth control pills, several studies have shown that most antibiotics do not increase the risk of pregnancy in women taking birth control pills. Nevertheless, there have been reports of birth control pill failure in women who have taken antibiotics. Ask your healthcare provider about whether or not you need a backup method of birth control. In many situations, it is better to use backup rather than to take any risk of an unintended pregnancy.
 
Bismuth Subsalicylate
Bismuth subsalicylate may decrease the absorption of minocycline. It is best to take minocycline at least two hours before or six hours after taking bismuth subsalicylate.
 
Ergot Medications
There is some concern that tetracycline antibiotics (like minocycline) might increase the side effects of ergot alkaloids. Check with your healthcare provider before taking such medications together.

Minocycline HCL

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