Nafcillin Side Effects

Side Effects to Report

Some side effects of nafcillin are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an overdose (which can occur even at normal dosages if a person has kidney or liver disease), such as:
    • Seizures
    • Coma
    • Unusual muscle movements or hyperactivity
  • Watery or bloody diarrhea (which may start while taking the drug or even quite a while after treatment ends), which can become quite dangerous
  • Irritation or inflammation at the injection or IV site, which is usually minor but occasionally can cause severe damage
  • Signs of kidney problems, such as:
    • A rash
    • Fever
    • High levels of eosinophils in the blood (found using a blood test)
    • Blood or protein in the urine (found using a urine test)
    • Decreased urine output
    • Low white blood cells (found using a blood test) or other low blood cell counts

  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Itching
    • Hives
    • Redness of the face
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using nafcillin or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.

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