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Plaquenil Interactions
When phenothiazine medications, certain beta blockers, or certain parasite medicines are taken together with Plaquenil, interactions can occur that may affect the drug levels in your blood. This could increase your risk for side effects or decrease the effectiveness of the medicines. To help prevent potentially negative Plaquenil drug interactions, tell your healthcare provider about all other medications you are taking before starting Plaquenil.
Plaquenil® (hydroxychloroquine sulfate) can potentially interact with a few other medications. Some of these medicines that may lead to Plaquenil drug interactions include:
- Certain beta blockers, such as:
- Bisoprolol (Zebeta®)
- Metoprolol (Lopressor®, Toprol XL®)
- Propranolol (Inderal®)
- Sotalol (Betapace®)
- Timolol (Blocadren®)
- Carvedilol (Coreg®)
- Labetalol (Trandate®)
- Certain parasite medications, such as:
- Albendazole (Albenza®)
- Mebendazole (Vermox®)
- Praziquantel (Biltricide®)
- Thiabendazole (Mintezol®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Digoxin (Digitek®, Lanoxin®)
- Mefloquine (Lariam®)
- Phenothiazine medications, including:
- Chlorpromazine (Thorazine®)
- Fluphenazine (Prolixin®)
- Perphenazine (Trilafon®)
- Prochlorperazine (Compazine®, Compro®)
- Thioridazine (Mellaril®)
- Trifluoperazine (Stelazine®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD