More Information on Retapamulin's Indications

How Does Retapamulin Work?

Retapamulin works by inhibiting part of bacterial ribosomes, which are parts of cells that make proteins necessary for the bacteria to grow and multiply. The medicine specifically inhibits the 50S subunit of the ribosome. Because human cells do not have a 50S subunit, they are spared from the effects of the antibiotic.
Retapamulin works in a different way than other antibiotics that inhibit the 50S subunit, which means it is in a class by itself. In fact, it is the first in a new class of medications known as pleuromutilin antibiotics.

Retapamulin Use in Children

Retapamulin has been thoroughly studied in children as young as nine months old. It is not approved for use in younger infants, as it has not been adequately studied in that age group.
Talk with your child's healthcare provider about the benefits and risks of using retapamulin in children. For very young children, it is often beneficial to cover the treated area with a bandage or gauze in order to prevent licking of the ointment or spreading it to the eyes.

Is Retapamulin Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend this medication for something other than treating impetigo. Prescribing retapamulin to treat other types of skin infections or to prevent any type of infection would be an off-label use.
Retapamulin is approved only to treat impetigo caused by S. pyogenes or methicillin-sensitive S. aureus bacteria. Prescribing it to treat methicillin-resistant S. aureus (MRSA) infections is considered an off-label use for retapamulin.
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Retapamulin Medication Information

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