Suprax Warnings and Precautions

There are certain precautions that should be taken when using Suprax, such as following warnings regarding potential drug interactions, dangers for people who have kidney or liver problems, and risks for those who have certain allergies. Discussing your medical history with your healthcare provider can help to minimize your risk for potentially serious complications with this antibiotic.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Suprax® (cefixime) if you have:
 
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • An allergy to cephalosporin or penicillin antibiotics
  • Any other allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Suprax

Some warnings and precautions to be aware of prior to taking this medication include the following:
 
  • Suprax contains an antibiotic that belongs to the cephalosporin group of antibiotics, which are related to penicillin antibiotics. Some people who are allergic to penicillin will also be allergic to Suprax. An allergic reaction can be quite dangerous.
 
Let your healthcare provider know immediately if you notice any signs of an allergic reaction, such as: 
    • A rash
    • Itching
    • Hives
    • Wheezing
    • Swelling of the mouth or lips
    • Difficulty breathing.
 
  • Make sure your healthcare provider knows if you have kidney disease, as the kidneys remove Suprax from the body. If your kidneys are not functioning well, you will need a lower and/or less-frequent dosage.
 
  • Let your healthcare provider know if you experience bloody or watery diarrhea. While diarrhea is a common side effect of Suprax, bloody or watery diarrhea may be a sign of a serious reaction that can occur when certain bacteria (Clostridium difficile) overgrow in the colon. This severe reaction can occur long after you stop using the drug and can be life-threatening.
 
  • Antibiotics, including Suprax, can sometimes cause yeast infections, as they can get rid of "good" bacteria that help protect against yeast infections. Let your healthcare provider know if you develop a vaginal yeast infection or thrush (a yeast infection of the mouth) during treatment.
 
  • Suprax should not be used to treat viruses, such as the common cold or the flu. This drug is completely ineffective for treating viruses, and such use can lead to bacterial resistance.
 
  • Suprax can impair the body's ability to form blood clots, especially in people who are already at risk for bleeding, including people with liver or kidney disease or people taking "blood thinners" (anticoagulants).
   
  • Suprax is a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are currently unknown. Talk to your healthcare provider about the risks and benefits of taking this medicine during pregnancy (see Suprax and Pregnancy for more information).
 
  • It is unknown if Suprax passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider prior to taking Suprax (see Suprax and Breastfeeding for more information).
 
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Suprax Medication Information

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