Important Instructions for Tetracycline

Tetracycline Dosage for Acne

The recommended tetracycline dosage for the treatment of moderate to severe acne is tetracycline 125 mg to tetracycline 500 mg twice daily. Acne treatment should be continued for at least 12 weeks for maximum benefit. As acne improves, your healthcare provider may decrease the dosage to 125 mg to 500 mg once daily.

Tetracycline Dosage for H. Pylori Infections

Treatment to kill Helicobacter pylori (H. pylori) involves using at least two other drugs besides tetracycline. The tetracycline dosage for killing H. pylori is 500 mg two to four times daily, depending on the regimen being used. In addition, an acid-suppressing H2-blocker or proton pump inhibitor and one or two other antibiotics will be used at the same time. Treatment is usually carried out for 10 to 14 days.

Other General Tetracycline Dosage Information

Some other information for people taking tetracycline includes:
  • Tetracycline should be taken at the same time each day to maintain an even level of the antibiotic in your system.
  • Tetracycline works best when taken without food, either one hour before eating or two hours after you have eaten. However, it can be taken with food if it upsets your stomach.
  • Drink a full glass of water with each dose.  


  • For tetracycline to work properly, you have to take it as prescribed.
  • Make sure that you complete your entire prescription of tetracycline, even if you start feeling better. This will ensure that the infection is completely treated.
  • Never take outdated tetracycline. This can cause serious problems, as outdated tetracycline can be toxic to the kidneys.
  • If you are unsure about anything related to tetracycline or your tetracycline dosage, please talk with your doctor, nurse, or pharmacist. Do not stop taking tetracycline without first discussing it with your healthcare provider.
A Dose of Reassurance for Parents of Picky Eaters

Tetracycline Hydrochloride

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