Medications That Can React With Vibramycin

More Information on Vibramycin Interactions

The following sections explain in detail the potentially negative interactions that can occur when Vibramycin is taken with any of the medications listed above.
Aluminum/Calcium/Magnesium/Iron Products
If Vibramycin is taken with products containing aluminum, calcium, magnesium, or iron, your body may not adequately absorb Vibramycin. To avoid this interaction, it is a good idea to take Vibramycin at least two hours before or six hours after any products with aluminum, calcium, magnesium, or iron.
Barbiturate medications may decrease the level of Vibramycin in the blood, perhaps making it less effective. Check with your healthcare provider before taking Vibramycin with a barbiturate.
Bile Acid Sequestrants
Bile acid sequestrants may bind to Vibramycin in the digestive tract, preventing it from being properly absorbed. This can make Vibramycin less effective. Separate your doses of Vibramycin and a bile acid sequestrant by as much time as possible (at least two hours or more).
Birth Control Pills
Despite the longstanding belief that antibiotics interact with birth control pills, several studies have shown that most antibiotics do not increase the risk of pregnancy in women taking birth control pills. Nevertheless, there have been reports of birth control pill failure in women who have taken antibiotics. Ask your healthcare provider about whether or not you need to use a backup method of birth control. In many situations, it is better to use backup rather than to take any risk of an unintended pregnancy.
This interaction is probably more of a concern with the newer, low-dose oral contraceptives.
Bismuth Subsalicylate
Bismuth subsalicylate may decrease the absorption of Vibramycin. It is best to take Vibramycin at least two hours before or six hours after taking bismuth subsalicylate.

Vibramycin Antibiotic Information

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