Zithromax Drug Interactions

Zithromax Drug Interactions Explained

The following sections explain in detail how the drugs mentioned above can cause potentially negative interactions when combined with Zithromax.
 
Warfarin (Coumadin, Jantoven)
If you are taking Zithromax and warfarin, your body may metabolize warfarin differently than intended, perhaps increasing the risk of bleeding. Your healthcare provider may choose to monitor your INR and prothrombin time more frequently and adjust accordingly. INR and prothrombin time are tests used to measure how well you blood is clotting.
 
Aluminum or Magnesium Antacids (Maalox, Mylanta, Riopan, Gelusil, Rolaids, ALternaGEL, Amphojel, and Others)
If you are taking both Zithromax and antacids made with aluminum or magnesium, Zithromax may not be absorbed into your body as well as normal. Be sure to take the antacids at least two hours before or two hours after taking Zithromax.
 
Digoxin (Digitek, Lanoxicaps, Lanoxin)
If you take Zithromax with digoxin, your body may metabolize digoxin differently than intended, perhaps increasing the risk of digoxin toxicity. Discuss this with your healthcare provider prior to starting Zithromax.
 
Tacrolimus (Prograf, Protopic)
If you are taking Zithromax and tacrolimus together, your body may metabolize tacrolimus differently than intended and significantly increase the level of the drug in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.
 
Cyclosporine (Gengraf, Neoral, Sandimmune, Restasis)
If you are taking both Zithromax and cyclosporine, your body may metabolize cyclosporine differently than intended and significantly increase the drug level in your system. Your healthcare provider may choose to monitor your progress and adjust your dose accordingly.
(Zithromax Drug Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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