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Zithromax Drug Interactions
Among the drugs that can potentially interact with Zithromax are cyclosporine, triazolam, and antacids containing aluminum or magnesium (such as Maalox or Rolaids). These reactions can cause your body to metabolize the medicines differently than intended, cause an increase in heart toxicity, and alter the levels of some drugs in your system, among other things.
Zithromax® (azithromycin) can potentially interact with a number of other medicines. Drugs that can interfere with Zithromax include but are not limited to:
- Medications that cause a heart rhythm change known as QT prolongation (see QT-Prolonging Medications for a list)
- Warfarin (Coumadin®, Jantoven®)
- Antacids containing aluminum or magnesium, such as Maalox®, Mylanta®, Riopan®, Gelusil®, Rolaids®, ALternaGEL®, Amphojel®, and others
- Digoxin (Digitek®, Lanoxicaps®, Lanoxin®)
- Tacrolimus (Prograf®, Protopic®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®, Restasis®)
- Phenytoin (Dilantin®, Phenytek™)
- Triazolam (Halcion®)
- Ergot alkaloids
- Theophylline (Elixophyllin®, Theo-24®, Uniphyl®, TheoCap™, Theochron®)
- Carbamazepine (Carbatrol®, Epitol®, Tegretol®, Tegretol®-XR, Equetro™)
- Nelfinavir (Viracept®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD